
Michael Andregg
Founder building optical compute and brainâemulation technology
michaelandregg
San Francisco, California
Joined October 2025
Network
11.8K connectionsJBRKGW
AIRKGI
TWSHAG
DSVMDL
UIASSE
DBJGSL
LSCPAS
Summary
Serial hardwareâfirst founder focusing on ambitious, instrumentâlevel problems: Andregg has repeatedly founded and led startups that build physical systems â from Halcyon Molecular's electronâmicroscopy DNAâsequencing instrumentation to optics and photonics work at Fathom Computing and Fathom Radiant, and now Eon Systems (brainâscale mapping/emulation). His track record shows emphasis on endâtoâend hardware development, prototyping, and taking risky physical R&D projects from lab prototypes toward company formation. justia+2
Handsâon biological and instrumentation experience: multiple conference papers and patents tie Andregg to wetâlab and microscopy techniques (molecular threading, EM imaging) as well as the instrumentation side (microfabrication, probe systems). He appears comfortable operating across biology, microscopy, and precision fabrication â a blend that informed Halcyon's sequencing work and later hardware efforts. researchgate+1
Interest and public engagement on longâtermist topics (WBE/whole brain emulation, AI compute and safety): Andregg participates in foresight/AI/longtermist communities (Foresight events, EA posts, signatory and public talks) and has publicly discussed compute and brainâscale mapping strategies, aligning recent work (Eon Systems) with highâambition goals around brain emulation. foresight+2
Named inventor on multiple patents spanning EMâbased sequencing and photonic computing: his inventorship on Halcyon patents and on Fathom Radiant/optics filings indicates a sustained technical contribution to both nanoscale imaging/sequencing and photonic compute hardware. justia+1
Work
Education
Projects
Writing
Wavelength Multiplexed MatrixâMatrix Multiplier (US publication US20180107237A1)
January 1, 2018Patent publication related to wavelengthâmultiplexed photonic matrixâmultiply approaches associated with Fathom Radiant.
Sequencing nucleic acid polymers with electron microscopy (US 8,153,438)
January 1, 2012Patent describing an approach to sequence DNA by labeling/stretched DNA and imaging with electron microscopy to read sequences directly.
Molecular threading / conference papers (Microscopy & Microanalysis; Microscopy and Microanalysis abstracts)
2011-2013Conference papers and abstracts describing apparatus and protocols for molecular threading (stretching and depositing single DNA molecules for EM imaging).
Hobbies
Cryonics, selfâarchivization, interest in wholeâbrain emulation, dodgeball and selfâimprovement (listed on a Halcyon slide / profile). newyorker
Similar profiles
NB
Nathan Benaich
Founder at Spinout.fyi
97.6K connections
RCRafael Cosman
Founder & CEO at Protogon Research
21K connections
ATAlex Teichman
Founder & CEO at Happenstance
14.8K connections
DSD. Scott Phoenix
Partner at Fifty Years
8.2K connections
AMAaron Mayer
Founder and Executive Director at Impact Labs
11.1K connections
NLnick linck
19.2K connections