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Gouranga Saha

Gouranga Saha

Biotechnology consultant and cancer biology researcher (PhD)

gourangasaha
Faridabad, Haryana, India
Joined February 2026

Network

334 connections
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Cancer Biology PIs
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RCB PhD Scholars
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Indian Chemical Biology
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European Research Leaders
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RCB Faculty PIs
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Cell Gene Therapy
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Rutgers Cancer

Summary

Biotechnology consultant (RCB, 2025–present) and senior cancer biology researcher (CSIR-IICB, 2017–2024) with a PhD in Biotechnology (University of Calcutta, 2017–2023), experienced in USP7 biology, glioma research, and nanoparticle-based translational strategies. res+2
Focused cancer biology researcher with multiple publications on USP7 and deubiquitination pathways. nih+2
Contributor to translational glioma research, including nanoparticle-based combinatorial therapies (TMZ + DIM) aimed at improving drug delivery across the blood–brain barrier. biorxiv+1
Experienced in collaborative, peer-reviewed research while affiliated with CSIR-IICB and transitioning to a technical consultant role at RCB. res+2
Maintains public researcher profiles (Google Scholar, ResearchGate, ResearchID) documenting citation impact and publication record. google+2

Work

Education

Writing

UPS and Kinases—Gatekeepers of the G1/S Transition

January 1, 2025

Review discussing coordination between ubiquitin–proteasome system (UPS) and kinases in regulating the G1/S cell-cycle transition and implications for cancer biology. Cited by 2.

Favicon imagepubmed.ncbi.nlm.nih.gov

Glioma nanotherapy: Unleashing the synergy of dual-loaded DIM and TMZ

September 1, 2024

Peer-reviewed article reporting that PLGA-based dual loading of TMZ and DIM enhances drug delivery across the blood–brain barrier, increases DNA damage and apoptosis, reduces tumor burden and systemic toxicity in preclinical glioma models. Cited by 12.

Favicon imagepubmed.ncbi.nlm.nih.gov

PLGA-based dual-loaded nanoformulation of DIM and TMZ - An advanced clinical strategy for brain cancer treatment in a combinatorial approach

May 1, 2023

Preprint describing development of a PLGA-based nanoparticle co-encapsulating Temozolomide and 3,3'-diindolylmethane (DIM) to enhance brain tumor drug delivery and therapeutic synergy in preclinical models. Cited by 6.

Favicon imagebiorxiv.org

USP7 - a crucial regulator of cancer hallmarks

April 1, 2023

Review summarizing USP7's roles across cancer hallmarks and discussing USP7-targeting strategies and inhibitor development challenges. Cited by 89.

Favicon imagepubmed.ncbi.nlm.nih.gov

A small HDM2 antagonist peptide and a USP7 inhibitor synergistically inhibit the p53-HDM2-USP7 circuit

April 1, 2023

Study reporting a helically constrained peptide that inhibits p53-HDM2 interaction and demonstrates synergistic anti-proliferative effects when combined with a USP7 inhibitor. Cited by 2.

Favicon imagepubmed.ncbi.nlm.nih.gov

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma

October 1, 2022

Research article identifying XIAP as a USP7 deubiquitination substrate and describing a p53-independent pathway by which USP7 promotes glioma progression; includes in vitro and in vivo combinatorial inhibition results. Cited by 32.

Favicon imagepubmed.ncbi.nlm.nih.gov

The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer

January 1, 2025

Review of vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer, discussing USP7-targeting strategies and implications for therapy. Cited by 9.

Favicon imagesciencedirect.com

USP7 (Ubiquitin-Specific Protease 7)

January 1, 2018

Encyclopedia chapter summarizing USP7's functions, regulatory mechanisms, and roles in cancer signaling pathways.

Favicon imagelink.springer.com

Cellular homeostasis or tumorigenesis: USP7 playing the double agent

January 1, 2018

Article discussing USP7's dual roles in maintaining cellular homeostasis and promoting tumorigenesis, highlighting context-dependent functions.

Favicon imagescispace.com

The regulation of deubiquitinase USP7 through various signaling network and its role in oncogenesis

Overview of regulatory mechanisms controlling USP7 and its role in oncogenesis.

Favicon imagescholar.google.com

Comprehensive insights on COVID-19 host-pathogen interactions

Book chapter detailing the mechanisms of host-pathogen interactions specifically related to COVID-19, contributing to understanding infection pathways and immune responses.

Favicon imageresearchgate.net

Advances in COVID-19 therapeutic strategies

A book chapter exploring recent advancements in therapeutic approaches to treat COVID-19, covering antiviral drugs, immunomodulators, and vaccine development.

Favicon imageresearchgate.net