Moaraj Hasan

A patent application detailing particles and methods for assaying.

A patent application describing an apparatus for biomolecule assay.

Demonstrates the importance of the protein to nanoparticle-surface ratio (P/NP) in modulating protein corona composition and enhancing the depth and precision of nanoparticle-based deep proteomic workflows. The study highlights how increasing binding competition on engineered nanoparticles identifies significantly more proteins and suggests P/NP plays a critical role in nanomedicine applications.

Describes a method for deep profiling of the plasma proteome using surface-functionalized superparamagnetic nanoparticles, achieving superior precision, depth, and throughput compared to traditional approaches. It details how machine learning is used to analyze nanoparticle physicochemical properties and protein corona composition.

Investigates the mitochondrial proteome across various tissues in a mouse population, quantifying and localizing proteins.

Focuses on evaluating the physicochemical properties of drug molecules through microsolvation measurements combined with differential mobility spectrometry.

Details the development of targeted interleukin-10 nanotherapeutics using a microfluidic chip, which improves the resolution of inflammation in advanced atherosclerosis.

Researches persistent intramolecular hydrogen-bonding in benzyl meldrum's acid derivatives, contributing to fundamental chemistry.