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Forrest Collman

Forrest Collman

Neuroscience Informatics Leader | Brain Connectomics | Data & Technology

Seattle, Washington, United States
Joined May 2024

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Summary

Forrest Collman is a leader in neuroscience informatics and connectomics at the Allen Institute, where he co-leads the electron microscopy connectomics project. His work involves developing and managing the computational infrastructure for processing petascale brain data, making it accessible and useful for a broad range of neuroscientists. alleninstitute+2
He is the creator of the Connectome Annotation Versioning Engine (CAVE), a significant computational tool for the dynamic proofreading, annotation, and analysis of large-scale electron microscopy datasets. This tool is critical for projects mapping the full connectivity of brains, including major initiatives like MICrONs and FlyWire. alleninstitute+1
Forrest has a strong background in experimental and computational neuroscience, bridging physics, molecular biology, and informatics. His foundational research includes developing two-photon microscopy methods for awake, behaving mice and virtual reality behavioral environments during his PhD at Princeton, as well as contributing to computational models of olfaction during his undergraduate studies. alleninstitute+1
His expertise extends to advanced imaging techniques, including the development and application of conjugate IF/SEM array tomography for studying neural plasticity during his postdoctoral research at Stanford and early career at the Allen Institute. This work has been crucial for understanding synaptic architecture at a detailed level. alleninstitute+1

Work

Education

Projects

Writing

CAVE: Connectome Annotation Versioning Engine

April 1, 2025

Details the Connectome Annotation Versioning Engine (CAVE), a computational tool essential for the dynamic proofreading, annotation, and analysis of large-scale electron microscopy datasets in connectomics.

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Functional connectomics spanning multiple areas of mouse visual cortex

January 1, 2025

A publication contributing to the understanding of neural circuits by leveraging advanced functional connectomics data.

Favicon imagescholar.google.com

Neuronal wiring diagram of an adult brain

January 1, 2024

A study detailing the complex neuronal wiring of an adult brain, likely contributing to projects like FlyWire.

Favicon imagescholar.google.com

Mapping synapses by conjugate light-electron array tomography

January 1, 2015

Describes methods for mapping synapses using advanced imaging techniques, a key area of Forrest Collman's work at Stanford and the Allen Institute.

Favicon imagescholar.google.com

Intracellular dynamics of hippocampal place cells during virtual navigation

January 1, 2009

Research on the internal cellular processes of hippocampal place cells, relevant to his PhD work on two-photon microscopy and virtual reality.

Favicon imagescholar.google.com

Rate-specific synchrony: using noisy oscillations to detect equally active neurons

January 1, 2008

His undergraduate senior thesis, exploring computational models of olfaction and neuronal synchrony.

Favicon imagemolbio.princeton.edu

Imaging large-scale neural activity with cellular resolution in awake, mobile mice

January 1, 2007

A foundational paper on imaging neural activity in live, mobile subjects, stemming from his PhD research.

Favicon imagescholar.google.com

Notes

ATAlex Teichmansaid they've seen
FCForrest Collman
use their AI expertise to benefit nonprofit organizations in a meaningful way.

Dec 13, 2025