
Michael Andregg
Founder building optical compute and brain‑emulation technology
michaelandregg
San Francisco, California
Joined October 2025
Network
11.7K connectionsJBHZB
RGVMPB
DAEBLC
UIASMW
WASHAG
HZJSMB
RKAD
Summary
Serial hardware‑first founder focusing on ambitious, instrument‑level problems: Andregg has repeatedly founded and led startups that build physical systems — from Halcyon Molecular's electron‑microscopy DNA‑sequencing instrumentation to optics and photonics work at Fathom Computing and Fathom Radiant, and now Eon Systems (brain‑scale mapping/emulation). His track record shows emphasis on end‑to‑end hardware development, prototyping, and taking risky physical R&D projects from lab prototypes toward company formation. justia+2
Hands‑on biological and instrumentation experience: multiple conference papers and patents tie Andregg to wet‑lab and microscopy techniques (molecular threading, EM imaging) as well as the instrumentation side (microfabrication, probe systems). He appears comfortable operating across biology, microscopy, and precision fabrication — a blend that informed Halcyon's sequencing work and later hardware efforts. researchgate+1
Interest and public engagement on long‑termist topics (WBE/whole brain emulation, AI compute and safety): Andregg participates in foresight/AI/longtermist communities (Foresight events, EA posts, signatory and public talks) and has publicly discussed compute and brain‑scale mapping strategies, aligning recent work (Eon Systems) with high‑ambition goals around brain emulation. foresight+2
Named inventor on multiple patents spanning EM‑based sequencing and photonic computing: his inventorship on Halcyon patents and on Fathom Radiant/optics filings indicates a sustained technical contribution to both nanoscale imaging/sequencing and photonic compute hardware. justia+1
Work
Education
Projects
Writing
Wavelength Multiplexed Matrix‑Matrix Multiplier (US publication US20180107237A1)
January 1, 2018Patent publication related to wavelength‑multiplexed photonic matrix‑multiply approaches associated with Fathom Radiant.
Sequencing nucleic acid polymers with electron microscopy (US 8,153,438)
January 1, 2012Patent describing an approach to sequence DNA by labeling/stretched DNA and imaging with electron microscopy to read sequences directly.
Molecular threading / conference papers (Microscopy & Microanalysis; Microscopy and Microanalysis abstracts)
2011-2013Conference papers and abstracts describing apparatus and protocols for molecular threading (stretching and depositing single DNA molecules for EM imaging).
Hobbies
Cryonics, self‑archivization, interest in whole‑brain emulation, dodgeball and self‑improvement (listed on a Halcyon slide / profile). newyorker
Similar profiles
NB
Nathan Benaich
Founder at Spinout.fyi
97.3K connections
RCRafael Cosman
Founder & CEO at Protogon Research
20.9K connections
ATAlex Teichman
Founder & CEO at Happenstance
14.8K connections
DSD. Scott Phoenix
Partner at Fifty Years
8.2K connections
AMAaron Mayer
Founder and Executive Director at Impact Labs
11.1K connections
NLnick linck
18.1K connections