
Clayton Bryan
Partner at 500 Global β Head of Global Accelerator Fund
San Francisco, California
Joined January 2025
Network
3.7K connectionsAAPSET
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Summary
Early-stage investor and accelerator operator: Clayton has built his career around running and improving accelerator programs and deploying early-stage capital globally. At 500 Global he leads the flagship accelerator and the Global Accelerator Fund, which focuses on sourcing, structuring, and supporting seed-stage investments across sectors like AI, health, commerce, and fintech. 500+2
Committed to increasing access for underrepresented founders: Clayton co-founded Transparent Collective to prepare and connect minority founders with investors and mentors. That work β plus programming and public speaking on inclusion β is a through-line in his career from NewMe to Transparent Collective to his work at 500 Global. transparentcollective+1
Operator background in community, product, and growth: Before VC and accelerator leadership, Clayton worked in product/community roles (Yahoo, Howcast, Payvment) and growth/corporate development at consumer/startup products β experience he applies when advising marketplace and consumer founders. techcrunch+1
Board & advisory leadership in ecosystem organizations: Beyond investing, Clayton holds governance and advisory roles (NYU Entrepreneurial Institute, ICA Fund), connecting university entrepreneurship programming and nonprofit venture efforts with practitioner experience. nyu+1
Work
Education
Projects
Writing
500 Global interview: Clayton Bryan on doubling down on founders
January 1, 2023Longer Q&A-style interview on 500 Global's site describing his background, investment focus, and approach to accelerator programming and founder support.
Articles and posts by Clayton Bryan (TechCrunch author page)
Collection of commentary and posts on startup investing, accelerator strategy, and founder advice published under his author profile at TechCrunch.
Notes
TPTristan Pollocksaid
CBClayton Bryan
is someone they consider especially well-connected and respected in their industry.Nov 26, 2025
TPTristan Pollocksaid
CBClayton Bryan
represents what makes the 500 Global alumni network special or high-caliber.Nov 21, 2025
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