
Mike Spadafore
Healthcare Investor, Managing Director, and Board Member
mikespadafore
Greater Chicago Area
Joined August 2025
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Summary
Mike Spadafore is a dedicated healthcare investor and operating partner with over 15 years of experience, currently serving as a Managing Director at Valtruis and an Operating Partner at WCAS. He focuses on working with entrepreneurs and executives in the healthcare and technology sectors to drive value-based care initiatives. valtruis+2
Before joining Valtruis, Mike was a Managing Director at the Blue Venture Fund and Sandbox Industries, where he played a key role in investment strategy, portfolio management, and engagement with Blue Plan executives. His board memberships included companies like ID Experts, Prove, Physera, Wellframe, WiderCircle, Abacus Insights, and Workit Health. harvard+3
Mike has a strong background in management consulting, having worked at PwC and Diamond Management and Strategy Consulting, specializing in IT strategy for health plans. He also founded Sandbox Advisors, a strategy and transaction consulting firm for healthcare clients. valtruis+1
His expertise extends to board roles in various healthcare technology companies, including Atropos Health and Autonomize AI, and he is listed as faculty for Executive and Continuing Education at the Harvard T.H. Chan School of Public Health, indicating his ongoing involvement in health innovation and education. autonomize+3
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Has a passion for exploring the world. clay
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