Arne Fabritius
Science Director and protein-engineering researcher focused on biosensors
Munich, Germany
Summary
Experienced protein-engineering researcher focused on developing genetically encoded biosensors and directed-evolution workflows; contributed to sensor design, large-scale screening platforms, and validation in cellular and in vivo systems. nih+2
Bridges research and application by building high-throughput analysis and sequencing workflows to support protein diversification and candidate selection for biosensor projects. github+1
Applies design, data visualization and scientific illustration to improve communication of complex biological concepts and to train researchers (runs a scientific-illustration masterclass and provides science communication consultancy). sci-illustrate+1
Combines academic research experience (doctoral and postdoctoral work at Max Planck-related groups) with industry-facing consultancy as Science Director at Endosymbiont GmbH. uni-muenchen+2
Work
Education
Projects
Writing
Fluorescent sensors for imaging of interstitial calcium
January 1, 2023Describes the design, validation and application of ultra-low affinity genetically encoded calcium biosensors (GreenT-ECs) tuned to interstitial/extracellular calcium concentrations and validated in neurons and zebrafish in vivo.
Novel genetically encoded biosensors for cGMP (Doctoral dissertation)
January 1, 2016Doctoral thesis on the development of genetically encoded biosensors for cGMP, completed as a dissertation at LMU Munich.
Design and directed evolution of genetically encoded cGMP sensors
January 1, 2015Presents an approach combining rational design and directed evolution to develop FRET-based cGMP biosensors, including semiautomatic high-throughput screening in E. coli and characterization of promising candidates.