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Brian Lawrence

Brian Lawrence

Founder & CEO developing silk‑derived protein therapeutics for ocular disease

brian
Lewis Center, Ohio
Plymouth, Minnesota
Joined May 2025
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Summary

Translational entrepreneur who spun PhD research into companies and clinical programs: Brian founded SilkTech (Silk Technologies) to commercialize silk‑derived protein (SDP) technology he studied in graduate work, has served as CEO since 2013, and led IND submission and Phase‑2 clinical development of SDP‑4 (Amlisimod) for dry eye disease. silk-tech+1
Technical inventor and IP leader in silk‑based biomaterials: public records and company materials show Dr. Lawrence as an inventor on patent filings related to silk‑derived protein formulations (e.g., WO2021141672) and describe a multi‑patent portfolio and numerous publications stemming from his work on silk fibroin and SDP technologies. google+1
Clinical and regulatory experience executing human studies: under his leadership SilkTech achieved IND clearance and initiated a randomized Phase‑2 trial of SDP‑4, and later completed enrollment in a Phase‑2b study, demonstrating experience in translating formulation science into regulated clinical development. medicalalley+1
Active in founder communities and industry engagement: Brian is involved with founder networks (StartX, Pando) and presents at eyecare and entrepreneurship events (Vision Expo, academic seminars), indicating a blend of scientific leadership, fundraising/partnering and community mentorship. osu+2

Work

Education

Projects

Writing

WO2021141672A2 — Stable formulations of silk‑derived protein

July 1, 2021

International patent application describing stable ophthalmic formulations containing silk‑derived protein (SDP‑4), formulation examples, stability data and approaches to maintain protein solubility and stability in eye drop formats.

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