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Avinash Karkada Ashok

Avinash Karkada Ashok

Computational biologist focused on bioinformatics and omics analytics

avinashkarkada
Baltimore, Maryland
Joined May 2026
Favicon imageavinashkarkada.github.io
Favicon imagegithub.com
Favicon imageorcid.org

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Summary

Computational biology practitioner with strong bioinformatics and omics analytics skills — blends NGS/immune profiling, statistical analysis, and ML-driven methods to analyze complex biological datasets and build reproducible pipelines. github+1
Experience spanning academia and industry — has contributed to academic publications on viral evolution, immunology and molecular modeling while also implementing production-oriented analysis pipelines and tooling in industry internships. asm+2
Emphasis on reproducibility and software engineering for research — develops workflow tools, containerized pipelines, and HPC/cloud-ready software to ensure analyses are shareable and performant. github+1
Published researcher in computational molecular biology and immunology — coauthor on peer-reviewed and preprint works covering viral host adaptation, RHIM-mediated cell death programs, quorum-sensing inhibitor discovery, and computational-experimental integrative studies. nih+2

Work

Education

Projects

Writing

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential

January 1, 2025

Analysis of viral protein adaptations in the 2.3.4.4b H5N1 clade across avian and diverse non-human mammalian hosts to evaluate mutations linked to human adaptive potential and host-specific selection patterns.

Favicon imagejournals.asm.org

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

January 1, 2024

Study describing viral RHIM motifs in bat-origin RNA viruses (including SARS-CoV-2 Nsp13) that modulate ZBP1-RIPK3 signaling and species-specific cell death programs.

Favicon imagepmc.ncbi.nlm.nih.gov

Computational-driven discovery of AI-2 quorum sensing inhibitor targeting the 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) to combat drug-resistant Helicobacter pylori

January 1, 2024

Computational screening and molecular dynamics characterization of compounds targeting MTAN to identify potential quorum sensing inhibitors for H. pylori.

Favicon imagepubmed.ncbi.nlm.nih.gov

Anti-enzymatic and DNA docking studies of montelukast: A multifaceted molecular scaffold with in vitro investigations, molecular expression analysis and molecular dynamics simulations

January 1, 2024

Combined in vitro enzyme inhibition assays and computational docking/MD simulations exploring montelukast's multi-target biochemical interactions and potential repurposing avenues.

Favicon imagepmc.ncbi.nlm.nih.gov

Antiurease Activity of Antibiotics: In Vitro, In Silico, Structure Activity Relationship, and MD Simulations of Cephalosporins and Fluoroquinolones

January 1, 2024

Integrated experimental and computational analysis investigating anti-urease activity of antibiotic classes, including docking and MD simulations.

Favicon imagedoi.org