Kyle Ferber
Associate Director, Biostatistics at Biogen
Summary
Work
Education
Projects
Writing
Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks
January 1, 2025Consortium study modeling timing of plasma biomarker changes (Aβ ratios, p-tau, GFAP, NfL) relative to amyloid and tau PET positivity using ADNI data; Kyle Ferber credited with data curation and formal analysis.
Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays
January 1, 2025Comparative study of five immunoassays for neurofilament light (NfL) measuring precision, parallelism, bias, and the ability to distinguish controls from individuals with ALS; Kyle Ferber is one of the authors affiliated with Biogen's biostatistics/biomarkers group.
Pharmacodynamic Effects of Litifilimab in Lupus in a Randomized, Placebo-Controlled Phase 2 Study
January 1, 2025Phase 2 randomized, placebo-controlled study of litifilimab in lupus indicating rapid and sustained reductions in type I interferon-associated gene expression and cytokines; Kyle Ferber appears among authors (Biogen affiliation).
Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice
November 1, 2024Preclinical study reporting dorsal root ganglion toxicity after AAV intra-CSF delivery of an RNAi construct; Kyle Ferber is listed among the authors with Biogen affiliation.
Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity
January 1, 2023Multi-center evaluation of plasma Aβ assays and their predictive performance for PET amyloid positivity; Kyle Ferber is listed among contributing authors affiliated with Biogen.
Derivation of a Three Biomarker Panel to Improve Diagnosis in Patients with Mild Traumatic Brain Injury
November 1, 2017Study deriving a three-biomarker blood panel (including neurogranin and other proteins) to improve diagnosis of mild traumatic brain injury; Kyle Ferber is listed among the authors/affiliations.
Modeling Discrete Survival Time Using Genomic Feature Data
January 1, 2015Paper presenting methods for modeling discrete survival time with genomic feature data (methodological work in biostatistics / genomic prediction).