Jason Fontana
Co-founder & CEO at Wayfinder Biosciences, pioneering RNA-targeting therapies
Summary
Work
Education
Projects
Writing
Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling
January 1, 2024This publication focuses on designing guide RNA structures to enable combinatorial CRISPRa programs, which are utilized for biosynthetic profiling.
Effective CRISPRa-mediated control of gene expression in bacteria must overcome strict target site requirements
January 1, 2020This research investigates the challenges and solutions for achieving effective CRISPRa-mediated gene expression control in bacteria, particularly concerning target site requirements.
CRISPR-Cas activation for regulating multi-gene expression in bacteria
January 1, 2020This doctoral dissertation explores the use of CRISPR-Cas activation for the regulation of multi-gene expression within bacterial contexts.
Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria
January 1, 2018This paper describes the development of synthetic CRISPR-Cas gene activators that allow for transcriptional reprogramming in bacterial systems.
Integrating artificial with natural cells to translate chemical messages that direct E. coli behaviour
January 1, 2014This publication details research on integrating artificial and natural cells to enable chemical communication, influencing the behavior of E. coli.