Luke M. Oltrogge

Large‑scale biochemical mapping of Rubisco variants and kinetic parameters; collaborative work contributing to an atlas of Rubisco function and evolution.

Demonstrates that the disordered scaffolding protein CsoS2 specifies α‑carboxysome size via repeat motifs that modulate shell curvature and mechanics; combines biochemical reconstitution, imaging, and modeling to propose a size‑control model.

Structural work showing the internal organization of Rubisco inside α‑carboxysomes, informing how packing and organization contribute to carboxysome function.

Describes how multivalent binding between the scaffold CsoS2 and Rubisco drives formation of α‑carboxysomes, providing mechanistic insight into cargo–scaffold interactions central to microcompartment assembly.